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KMID : 0391520040120020229
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Journal of the Korean Child Neurology Society
2004 Volume.12 No. 2 p.229 ~ p.234
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A Case of Basal Ganglia Infarct Associated with SLE.
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Cheong Hee-Young
Yoon Hee-Chul
Suh Eun-Sook
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Abstract
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Systemic lupus erythematosus(SLE), a rheumatic disease of unknown causes, is characterized by autoantibodies directed against self-antigens, resulting in inflammatory damages to target organs including kidney, blood-forming cells, and central nervous system. The prevalence rates are higher in Native Americans, Asians, Latin Americans and black people. A female to male ratio of approximately 2 : 1 occurs before puberty, and 4 : 1 after puberty. Children of SLE most frequently present with fever, fatigue, arthralgia or arthritis, and rashes. The diagnosis is confirmed by clinical and also laboratory manifestations satisfying at least 4 out of 11 criteria. A central nervous system is not rarely involved in children of SLE with the prevalence rate of 23-44%. However, cerebral infarcts are not a common phenomenon and can be seen only for 6% of children with SLE. There have been no cases reported in Korea. This is why we present a case of basal ganglia infarct associated with SLE in a 19-month old girl. We report this case with a brief review of related literature.
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KEYWORD
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Systemic lupus erythematosus, Basal ganglia infarct, Cerebrovascular disease
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